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Gravimetric measurement of antiperspirant effect / sweating study

Antiperspirants influence the activity of the sweat glands and thus reduce the formation of sweat. There are various approaches and methods for claim support of an antiperspirant effect. In most cases, the products to be tested are applied to the armpits of volunteers over several days. Afterwards, the subjects have to sweat under defined conditions. The amount of sweat in the test area (treated and untreated armpit) is absorbed by pads and analysed gravimetrically immediately after the sweating phases.

Whether according to FDA guidelines (Guidelines for Effectiveness Testing of OTC Antiperspirant Drug Products) or tailor made protocols – for the effectiveness testing of antiperspirant products, a product must achieve a significant reduction in sweat. The statistical analysis of the data is combined with descriptive statistics to provide appropriate documentation (expert opinion).

Depending on the customer’s requirements, test person collectives can be individually compiled and execution times variably adapted to the respective test product.

We have several hot rooms available for different studies. In addition, corresponding tests can also be carried out under more stringent conditions in an in-house sauna.


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